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Characterization of 15 single nucleotide polymorphism markers for chimpanzees (Pan troglodytes)

Here we report 15 new single nucleotide polymorphism markers for the the threatened Chipanzee that span both Y chromosome and autosomal regions of the genome.

Molecular evidence of tuberculosis induced hypertophic osteopathy in a 16th-century Iroquoian dog

Here we report on the oldest known case of TB to be discovered in domestic dogs and highlight their role as potential reservoirs of TB in the Americas.

Unreliable mtDNA data due to nuclear insertions: a cautionary tale from analysis of humans and other great apes

An analysis on the possible pitfalls 'numts' represent to mitochondrial DNA barcode data. We show that gorillas are particularly notable for possessing a ...

Nuclear Gene Sequences from a Late Pleistocene Sloth Coprolite

Here we show that nuclear DNA can be recovered from non-permafrost remains, but amplifying one multicopy and three single-copy nuclear gene fragments from a ...

The Genetic Secrets Some Fossils Hold

Here we summarize screening approaches that can identify well-preserved specimens for ancient DNA analysis.

Molecular Coproscopy: Dung and Diet of the Extinct Ground Sloth Nothrotheriops shastensis

Here we show a chemical agent, N-enacylthiazolium bromide, which cleaves cross-links between reducing sugars and amino groups making it possible for DNA ...

New software opens doors for biologists working with publicly available data.

Research software from McMaster provides new avenues for geneticists to access and interpret datasets from the National Centre for Biotechnology Information ...

Sequencing the complete genomes of two Siberian woolly mammoths

With an international team of collaborators, the McMaster Ancient DNA Centre is pleased to report the first complete genome sequences of two Siberian woolly ...

Gene diversity patterns at 10 X-chromosomal loci in humans and chimpanzees

Here we report a cross-species comparison of 10 X-chromosomal genes known to cause mental retardation in humans. Overall nucleotide diversity in these genes is ...

Genetic Discontinuity between the Maritime Archaic and Beothuk Populations in Newfoundland, Canada

By examining the mitochondrial genome diversity and isotopic ratios of 74 ancient remains in conjunction with the archaeological record, we have provided ...